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Invasive lobular breast carcinoma

MedGen UID:
75994
Concept ID:
C0279565
Neoplastic Process
Synonyms: breast invasive lobular carcinoma; Classic Invasive Lobular Carcinoma; classic invasive lobular carcinoma; Infiltrating Lobular Adenocarcinoma; infiltrating lobular adenocarcinoma; Infiltrating Lobular Breast Carcinoma; infiltrating lobular breast carcinoma; Infiltrating Lobular Carcinoma of Breast; infiltrating lobular carcinoma of breast; Infiltrating Lobular Carcinoma of the Breast; infiltrating lobular carcinoma of the breast; Invasive Breast Lobular Carcinoma; Invasive Lobular Adenocarcinoma; invasive lobular adenocarcinoma; Invasive Lobular Breast Carcinoma; invasive lobular breast carcinoma; Invasive Lobular Carcinoma; invasive lobular carcinoma; Invasive Lobular Carcinoma of Breast; invasive lobular carcinoma of breast; Invasive Lobular Carcinoma of the Breast; invasive lobular carcinoma of the breast; Invasive Lobular Carcinoma, Classic Type; invasive lobular carcinoma, classic type
 
Monarch Initiative: MONDO:0005051

Definition

An infiltrating lobular adenocarcinoma of the breast. The malignant cells lack cohesion and are arranged individually or in a linear manner (Indian files), or as narrow trabeculae within the stroma. The malignant cells are usually smaller than those of ductal carcinoma, are less pleomorphic, and have fewer mitotic figures. [from NCI]

Professional guidelines

PubMed

Birla R, Dinu D, Iosif C, Constantinoiu S
Chirurgia (Bucur) 2019 Sept-Oct;114(5):571-578. doi: 10.21614/chirurgia.114.5.571. PMID: 31670632
Chen XH, Zhang WW, Wang J, Sun JY, Li FY, He ZY, Wu SG
Biomark Med 2019 Feb;13(2):83-93. Epub 2018 Dec 19 doi: 10.2217/bmm-2018-0396. PMID: 30565472
Skotnicki P, Sas-Korczynska B, Wohadlo L, Jakubowicz J, Blecharz P, Reinfuss M, Walasek T
Eur J Gynaecol Oncol 2016;37(5):666-670. PMID: 29787007

Recent clinical studies

Etiology

Deberti M, Goupille C, Arbion F, Vilde A, Body G, Ouldamer L
J Gynecol Obstet Hum Reprod 2023 Dec;52(10):102665. Epub 2023 Sep 20 doi: 10.1016/j.jogoh.2023.102665. PMID: 37734568
Liu YL, Choi C, Lee SM, Zhong X, Hibshoosh H, Kalinsky K, Connolly EP
Clin Breast Cancer 2018 Apr;18(2):114-120. Epub 2017 Jun 23 doi: 10.1016/j.clbc.2017.06.006. PMID: 28720418
Skotnicki P, Sas-Korczynska B, Wohadlo L, Jakubowicz J, Blecharz P, Reinfuss M, Walasek T
Eur J Gynaecol Oncol 2016;37(5):666-670. PMID: 29787007
Chung MA, Cole B, Wanebo HJ, Bland KI, Chang HR
Ann Surg Oncol 1997 Oct-Nov;4(7):545-50. doi: 10.1007/BF02305534. PMID: 9367019
Poen JC, Tran L, Juillard G, Selch MT, Giuliano A, Silverstein M, Fingerhut A, Lewinsky B, Parker RG
Cancer 1992 Jun 1;69(11):2789-95. doi: 10.1002/1097-0142(19920601)69:11<2789::aid-cncr2820691126>3.0.co;2-j. PMID: 1571910

Diagnosis

Christgen M, Kandt LD, Antonopoulos W, Bartels S, Van Bockstal MR, Bredt M, Brito MJ, Christgen H, Colpaert C, Cserni B, Cserni G, Daemmrich ME, Danebrock R, Dedeurwaerdere F, van Deurzen CH, Erber R, Fathke C, Feist H, Fiche M, Gonzalez CA, Ter Hoeve ND, Kooreman L, Krech T, Kristiansen G, Kulka J, Laenger F, Lafos M, Lehmann U, Martin-Martinez MD, Mueller S, Pelz E, Raap M, Ravarino A, Reineke-Plaass T, Schaumann N, Schelfhout AM, De Schepper M, Schlue J, Van de Vijver K, Waelput W, Wellmann A, Graeser M, Gluz O, Kuemmel S, Nitz U, Harbeck N, Desmedt C, Floris G, Derksen PW, van Diest PJ, Vincent-Salomon A, Kreipe H
J Pathol Clin Res 2022 Mar;8(2):191-205. Epub 2021 Dec 10 doi: 10.1002/cjp2.253. PMID: 34889530Free PMC Article
Chen F, Ding K, Priedigkeit N, Elangovan A, Levine KM, Carleton N, Savariau L, Atkinson JM, Oesterreich S, Lee AV
Cancer Res 2021 Jan 15;81(2):268-281. Epub 2020 Nov 4 doi: 10.1158/0008-5472.CAN-20-0696. PMID: 33148662Free PMC Article
Swimley KM, Di Palma S, Thompson LDR
Head Neck Pathol 2021 Jun;15(2):642-648. Epub 2020 Jul 13 doi: 10.1007/s12105-020-01199-z. PMID: 32661671Free PMC Article
Birla R, Dinu D, Iosif C, Constantinoiu S
Chirurgia (Bucur) 2019 Sept-Oct;114(5):571-578. doi: 10.21614/chirurgia.114.5.571. PMID: 31670632
Liu YL, Choi C, Lee SM, Zhong X, Hibshoosh H, Kalinsky K, Connolly EP
Clin Breast Cancer 2018 Apr;18(2):114-120. Epub 2017 Jun 23 doi: 10.1016/j.clbc.2017.06.006. PMID: 28720418

Therapy

Riba LA, Russell T, Alapati A, Davis RB, James TA
J Surg Res 2019 Jan;233:436-443. Epub 2018 Sep 21 doi: 10.1016/j.jss.2018.08.011. PMID: 30502283
Du T, Sikora MJ, Levine KM, Tasdemir N, Riggins RB, Wendell SG, Van Houten B, Oesterreich S
Breast Cancer Res 2018 Sep 4;20(1):106. doi: 10.1186/s13058-018-1041-8. PMID: 30180878Free PMC Article
Tsung K, Grobmyer SR, Tu C, Abraham J, Budd GT, Valente SA
Am J Surg 2018 Mar;215(3):509-512. Epub 2017 Nov 14 doi: 10.1016/j.amjsurg.2017.11.011. PMID: 29197477
Liu YL, Choi C, Lee SM, Zhong X, Hibshoosh H, Kalinsky K, Connolly EP
Clin Breast Cancer 2018 Apr;18(2):114-120. Epub 2017 Jun 23 doi: 10.1016/j.clbc.2017.06.006. PMID: 28720418
Truin W, Vugts G, Roumen RM, Maaskant-Braat AJ, Nieuwenhuijzen GA, van der Heiden-van der Loo M, Tjan-Heijnen VC, Voogd AC
Ann Surg Oncol 2016 Jan;23(1):51-7. Epub 2015 May 16 doi: 10.1245/s10434-015-4603-3. PMID: 25980321Free PMC Article

Prognosis

Deberti M, Goupille C, Arbion F, Vilde A, Body G, Ouldamer L
J Gynecol Obstet Hum Reprod 2023 Dec;52(10):102665. Epub 2023 Sep 20 doi: 10.1016/j.jogoh.2023.102665. PMID: 37734568
Chen F, Ding K, Priedigkeit N, Elangovan A, Levine KM, Carleton N, Savariau L, Atkinson JM, Oesterreich S, Lee AV
Cancer Res 2021 Jan 15;81(2):268-281. Epub 2020 Nov 4 doi: 10.1158/0008-5472.CAN-20-0696. PMID: 33148662Free PMC Article
Liu YL, Choi C, Lee SM, Zhong X, Hibshoosh H, Kalinsky K, Connolly EP
Clin Breast Cancer 2018 Apr;18(2):114-120. Epub 2017 Jun 23 doi: 10.1016/j.clbc.2017.06.006. PMID: 28720418
Skotnicki P, Sas-Korczynska B, Wohadlo L, Jakubowicz J, Blecharz P, Reinfuss M, Walasek T
Eur J Gynaecol Oncol 2016;37(5):666-670. PMID: 29787007
Poen JC, Tran L, Juillard G, Selch MT, Giuliano A, Silverstein M, Fingerhut A, Lewinsky B, Parker RG
Cancer 1992 Jun 1;69(11):2789-95. doi: 10.1002/1097-0142(19920601)69:11<2789::aid-cncr2820691126>3.0.co;2-j. PMID: 1571910

Clinical prediction guides

Deberti M, Goupille C, Arbion F, Vilde A, Body G, Ouldamer L
J Gynecol Obstet Hum Reprod 2023 Dec;52(10):102665. Epub 2023 Sep 20 doi: 10.1016/j.jogoh.2023.102665. PMID: 37734568
Christgen M, Kandt LD, Antonopoulos W, Bartels S, Van Bockstal MR, Bredt M, Brito MJ, Christgen H, Colpaert C, Cserni B, Cserni G, Daemmrich ME, Danebrock R, Dedeurwaerdere F, van Deurzen CH, Erber R, Fathke C, Feist H, Fiche M, Gonzalez CA, Ter Hoeve ND, Kooreman L, Krech T, Kristiansen G, Kulka J, Laenger F, Lafos M, Lehmann U, Martin-Martinez MD, Mueller S, Pelz E, Raap M, Ravarino A, Reineke-Plaass T, Schaumann N, Schelfhout AM, De Schepper M, Schlue J, Van de Vijver K, Waelput W, Wellmann A, Graeser M, Gluz O, Kuemmel S, Nitz U, Harbeck N, Desmedt C, Floris G, Derksen PW, van Diest PJ, Vincent-Salomon A, Kreipe H
J Pathol Clin Res 2022 Mar;8(2):191-205. Epub 2021 Dec 10 doi: 10.1002/cjp2.253. PMID: 34889530Free PMC Article
Liu YL, Choi C, Lee SM, Zhong X, Hibshoosh H, Kalinsky K, Connolly EP
Clin Breast Cancer 2018 Apr;18(2):114-120. Epub 2017 Jun 23 doi: 10.1016/j.clbc.2017.06.006. PMID: 28720418
Homer N, Jakobiec FA, Stagner A, Cunnane ME, Freitag SK, Fay A, Yoon MK
Clin Exp Ophthalmol 2017 Aug;45(6):606-612. Epub 2017 Mar 3 doi: 10.1111/ceo.12926. PMID: 28181367
Skotnicki P, Sas-Korczynska B, Wohadlo L, Jakubowicz J, Blecharz P, Reinfuss M, Walasek T
Eur J Gynaecol Oncol 2016;37(5):666-670. PMID: 29787007

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