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Dissociative disorder

MedGen UID:
3871
•Concept ID:
C0012746
•
Mental or Behavioral Dysfunction
Synonyms: Disorder, Dissociative; Disorders, Dissociative; Dissociative Disorder; Dissociative Disorders; Dissociative Reaction; Dissociative Reactions; Reaction, Dissociative; Reactions, Dissociative
SNOMED CT: Dissociative disorder (44376007)
 
HPO: HP:0032940
Monarch Initiative: MONDO:0001160

Definition

Disruption or detachment of certain aspects of one's normal psychological functioning typically involves a disconnection or separation from thoughts, feelings, sensations, memories, or one's sense of identity or reality. [from HPO]

Professional guidelines

PubMed

Barriers to accessing and continuing mental health treatment among individuals with dissociative symptoms.
Nester MS, Hawkins SL, Brand BL
Eur J Psychotraumatol 2022;13(1):2031594. Epub 2022 Feb 17 doi: 10.1080/20008198.2022.2031594. PMID: 35186217Free PMC Article
Adaptive immersive Virtual Environments as a treatment for depersonalization disorder.
Patrikelis P, Konstantakopoulos G, Messinis L, Alexoudi A, Stefanatou M, Nasios G, Gatzonis S
Psychiatriki 2021 Dec 20;32(4):317-327. Epub 2021 Aug 5 doi: 10.22365/jpsych.2021.032. PMID: 34390559
Dissociative identity disorder and schizophrenia: differential diagnosis and theoretical issues.
Foote B, Park J
Curr Psychiatry Rep 2008 Jun;10(3):217-22. doi: 10.1007/s11920-008-0036-z. PMID: 18652789

Recent clinical studies

Etiology

Symptoms of depersonalisation/derealisation disorder as measured by brain electrical activity: A systematic review.
Salami A, Andreu-Perez J, Gillmeister H
Neurosci Biobehav Rev 2020 Nov;118:524-537. Epub 2020 Aug 23 doi: 10.1016/j.neubiorev.2020.08.011. PMID: 32846163
Dissociation debates: everything you know is wrong.
Loewenstein RJ
Dialogues Clin Neurosci 2018 Sep;20(3):229-242. doi: 10.31887/DCNS.2018.20.3/rloewenstein. PMID: 30581293Free PMC Article
Dissociative sensibility disorders - A retrospective case series and systematic literature review.
Weber P, Erlacher R
Eur J Paediatr Neurol 2018 Jan;22(1):27-38. Epub 2017 Sep 1 doi: 10.1016/j.ejpn.2017.08.005. PMID: 28899586
Dissociative disorders in acute psychiatric inpatients in Taiwan.
Chiu CD, Meg Tseng MC, Chien YL, Liao SC, Liu CM, Yeh YY, Hwu HG, Ross CA
Psychiatry Res 2017 Apr;250:285-290. Epub 2017 Feb 2 doi: 10.1016/j.psychres.2017.01.082. PMID: 28189923
Mental disorders, treatment response, mortality and serum cholesterol: a new holistic look at old data.
Jakovljević M, Reiner Z, Milicić D
Psychiatr Danub 2007 Dec;19(4):270-81. PMID: 18000478

Diagnosis

Sleep-Related Dissociative Disorders.
Eiser AS
Sleep Med Clin 2024 Mar;19(1):159-167. Epub 2023 Nov 22 doi: 10.1016/j.jsmc.2023.10.003. PMID: 38368062
Nocturnal agitation: From sleep state dissociation to sleep-related dissociative state.
Lopez R, Micoulaud-Franchi JA, Peter-Derex L, Dauvilliers Y
Rev Neurol (Paris) 2023 Oct;179(7):675-686. Epub 2023 Aug 23 doi: 10.1016/j.neurol.2023.07.003. PMID: 37625976
Dissociative sensibility disorders - A retrospective case series and systematic literature review.
Weber P, Erlacher R
Eur J Paediatr Neurol 2018 Jan;22(1):27-38. Epub 2017 Sep 1 doi: 10.1016/j.ejpn.2017.08.005. PMID: 28899586
Dissociative disorders.
Kihlstrom JF
Annu Rev Clin Psychol 2005;1:227-53. doi: 10.1146/annurev.clinpsy.1.102803.143925. PMID: 17716088
Pseudoseizures.
Bowman ES
Psychiatr Clin North Am 1998 Sep;21(3):649-57, vii. doi: 10.1016/s0193-953x(05)70029-0. PMID: 9774802

Therapy

Functional MRI-based study of emotional experience in patients with psychogenic non-epileptic seizures: Protocol for an observational case-control study-EMOCRISES study.
Fauvé P, Tyvaert L, Husson C, Hologne E, Gao X, Maillard L, Schwan R, Banasiak C, El-Hage W, Hossu G, Hingray C
PLoS One 2022;17(1):e0262216. Epub 2022 Jan 7 doi: 10.1371/journal.pone.0262216. PMID: 34995332Free PMC Article
Association between affective disorders presenting before and during pregnancy and pre-term birth, considering socio-demographic factors, obstetric factors, health conditions, and use of medication.
Aliaga A, Cunillera O, Amador MDC, Aliaga M, Arquerons M, Almeda J
Aten Primaria 2019 Dec;51(10):626-636. Epub 2018 Nov 16 doi: 10.1016/j.aprim.2018.06.009. PMID: 30454957Free PMC Article
Reconsidering the autohypnotic model of the dissociative disorders.
Dell PF
J Trauma Dissociation 2019 Jan-Feb;20(1):48-78. Epub 2018 Mar 22 doi: 10.1080/15299732.2018.1451806. PMID: 29565750
Posttraumatic stress disorder and physical comorbidity among female children and adolescents: results from service-use data.
Seng JS, Graham-Bermann SA, Clark MK, McCarthy AM, Ronis DL
Pediatrics 2005 Dec;116(6):e767-76. doi: 10.1542/peds.2005-0608. PMID: 16322133
Pseudoseizures: an overview.
Volow MR
South Med J 1986 May;79(5):600-7. doi: 10.1097/00007611-198605000-00020. PMID: 3518074

Prognosis

Psychiatric and legal considerations in cases of Fetal Abduction by Maternal Evisceration.
Welner M, Burgess A, O'Malley KY
J Forensic Sci 2021 Sep;66(5):1805-1817. Epub 2021 Jun 22 doi: 10.1111/1556-4029.14788. PMID: 34156091
Dissociative sensibility disorders - A retrospective case series and systematic literature review.
Weber P, Erlacher R
Eur J Paediatr Neurol 2018 Jan;22(1):27-38. Epub 2017 Sep 1 doi: 10.1016/j.ejpn.2017.08.005. PMID: 28899586
Child abuse and neglect in complex dissociative disorder, abuse-related chronic PTSD, and mixed psychiatric samples.
Dorahy MJ, Middleton W, Seager L, Williams M, Chambers R
J Trauma Dissociation 2016;17(2):223-36. Epub 2015 Aug 14 doi: 10.1080/15299732.2015.1077916. PMID: 26275087
Mental disorders, treatment response, mortality and serum cholesterol: a new holistic look at old data.
Jakovljević M, Reiner Z, Milicić D
Psychiatr Danub 2007 Dec;19(4):270-81. PMID: 18000478
Psychopathology, hypnotizability, and dissociation.
Frischholz EJ, Lipman LS, Braun BG, Sachs RG
Am J Psychiatry 1992 Nov;149(11):1521-5. doi: 10.1176/ajp.149.11.1521. PMID: 1415819

Clinical prediction guides

Anger regulation in patients with functional neurological disorder: A systematic review.
van Dijl TL, Videler AC, Aben HP, Kop WJ
Gen Hosp Psychiatry 2024 May-Jun;88:30-47. Epub 2024 Mar 2 doi: 10.1016/j.genhosppsych.2024.02.014. PMID: 38458028
Nocturnal agitation: From sleep state dissociation to sleep-related dissociative state.
Lopez R, Micoulaud-Franchi JA, Peter-Derex L, Dauvilliers Y
Rev Neurol (Paris) 2023 Oct;179(7):675-686. Epub 2023 Aug 23 doi: 10.1016/j.neurol.2023.07.003. PMID: 37625976
Fibromyalgia and dissociative symptoms.
Duarte JM, Crow C, Antik A, Appiani F, Caride A
CNS Spectr 2019 Dec;24(6):605-608. doi: 10.1017/S1092852918001608. PMID: 30894235
Three dimensions of dissociative amnesia.
Dell PF
J Trauma Dissociation 2013;14(1):25-39. doi: 10.1080/15299732.2012.724762. PMID: 23282045
Psychopathology, hypnotizability, and dissociation.
Frischholz EJ, Lipman LS, Braun BG, Sachs RG
Am J Psychiatry 1992 Nov;149(11):1521-5. doi: 10.1176/ajp.149.11.1521. PMID: 1415819

Recent systematic reviews

Anger regulation in patients with functional neurological disorder: A systematic review.
van Dijl TL, Videler AC, Aben HP, Kop WJ
Gen Hosp Psychiatry 2024 May-Jun;88:30-47. Epub 2024 Mar 2 doi: 10.1016/j.genhosppsych.2024.02.014. PMID: 38458028
Stress response in dissociation and conversion disorders: A systematic review.
Boulet C, Lopez-Castroman J, Mouchabac S, Olié E, Courtet P, Thouvenot E, Abbar M, Conejero I
Neurosci Biobehav Rev 2022 Jan;132:957-967. Epub 2021 Nov 2 doi: 10.1016/j.neubiorev.2021.10.049. PMID: 34740754
Symptoms of depersonalisation/derealisation disorder as measured by brain electrical activity: A systematic review.
Salami A, Andreu-Perez J, Gillmeister H
Neurosci Biobehav Rev 2020 Nov;118:524-537. Epub 2020 Aug 23 doi: 10.1016/j.neubiorev.2020.08.011. PMID: 32846163
Dissociative sensibility disorders - A retrospective case series and systematic literature review.
Weber P, Erlacher R
Eur J Paediatr Neurol 2018 Jan;22(1):27-38. Epub 2017 Sep 1 doi: 10.1016/j.ejpn.2017.08.005. PMID: 28899586
Conversion disorder: A systematic review of current terminology.
Ding JM, Kanaan RA
Gen Hosp Psychiatry 2017 Mar-Apr;45:51-55. Epub 2016 Dec 24 doi: 10.1016/j.genhosppsych.2016.12.009. PMID: 28274339

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