PTB-Associated Splicing Factor

An RNA splicing factor that also binds DNA. It is essential for pre-mRNA spicing in the formation of early SPLICEOSOMES and catalytic step II. It binds specifically to polypyrimidine tracts in INTRONS and is involved in the regulation of ALTERNATIVE SPLICING by SIGNAL TRANSDUCTION PATHWAYS.

Year introduced: 2017 (1993)

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Tree Number(s): D12.776.157.725.829.282, D12.776.260.693, D12.776.664.962.829.282

MeSH Unique ID: D000072670

Entry Terms:

• PTB Associated Splicing Factor
• Splicing Factor, PTB-Associated
• PSF Splicing Factor
• Splicing Factor, PSF
• SFPQ Protein
• Polypyrimidine Tract-Binding Protein-Associated Splicing Factor
• Polypyrimidine Tract Binding Protein Associated Splicing Factor
• Splicing Factor Proline-Glutamine Rich Protein
• Splicing Factor Proline Glutamine Rich Protein

See Also:

• Polypyrimidine Tract-Binding Protein

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Carrier Proteins
RNA-Binding Proteins
RNA Splicing Factors
PTB-Associated Splicing Factor

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
DNA-Binding Proteins
PTB-Associated Splicing Factor

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Nucleoproteins
RNA-Binding Proteins
RNA Splicing Factors
PTB-Associated Splicing Factor