Protein Kinase C-alpha
A cytoplasmic serine threonine kinase involved in regulating CELL DIFFERENTIATION and CELLULAR PROLIFERATION. Overexpression of this enzyme has been shown to promote PHOSPHORYLATION of BCL-2 PROTO-ONCOGENE PROTEINS and chemoresistance in human acute leukemia cells.
Year introduced: 2006(1999)
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Subheadings:
Tree Number(s): D08.811.913.696.620.682.700.725.100, D12.776.476.563.725.100
MeSH Unique ID: D051571
Registry Number: EC 2.7.11.13
Entry Terms:
- Protein Kinase C(alpha)
- Protein Kinase C alpha
- PKC-alpha Serine-Threonine Kinase
- PKC alpha Serine Threonine Kinase
- Serine-Threonine Kinase, PKC-alpha