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Acyclovir
A GUANOSINE analog that acts as an antimetabolite. Viruses are especially susceptible. Used especially against herpes.
Year introduced: 1983
2'-O-glycyl acyclovir [Supplementary Concept]
water-soluble ester of acyclovir; RN given refers to parent cpd
Date introduced: February 17, 1984
Valacyclovir
A prodrug of acyclovir that is used in the treatment of HERPES ZOSTER and HERPES SIMPLEX VIRUS INFECTION of the skin and mucous membranes, including GENITAL HERPES.
Year introduced: 2019 (1994)
acyclovir-5'-(phenyl methoxy alaninyl)phosphate [Supplementary Concept]
structure in first source
Date introduced: August 15, 2000
1-O-hexadecylpropanediol-3-p-acyclovir [Supplementary Concept]
Date introduced: July 27, 2000
Ganciclovir
An ACYCLOVIR analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
Year introduced: 1990
tyrosylacyclovir [Supplementary Concept]
an acyclovir prodrug; structure in first source
Date introduced: January 12, 2005
gamma-glutamylacyclovir [Supplementary Concept]
1-O-hexadecylpropanediol-3-phosphoacyclovir [Supplementary Concept]
Date introduced: August 30, 2000
acyclovir beta-glucoside [Supplementary Concept]
Date introduced: April 16, 1999
diamminechloro(9-(2-hydroxyethoxymethyl)guan-7-yl)platinum(II) [Supplementary Concept]
Date introduced: June 16, 1998
acyclovir fluorophosphate [Supplementary Concept]
Date introduced: March 25, 1998
acyclovir phosphite [Supplementary Concept]
1-O-octadecyl-sn-glycero-3-phospho-acyclovir [Supplementary Concept]
structure given in first source
Date introduced: August 26, 1997
acyclovir diphosphate dimyristoylglycerol [Supplementary Concept]
Date introduced: January 17, 1994
acyclovir monophosphate-lactosaminated serum albumin conjugate [Supplementary Concept]
releases the phosphorylated drug in liver cells
Date introduced: July 5, 1989
desciclovir [Supplementary Concept]
active prodrug of acyclovir
Date introduced: July 13, 1984
9-carboxymethoxymethylguanine [Supplementary Concept]
metabolite of acyclovir
Date introduced: August 20, 1982
8-hydroxyacyclovir [Supplementary Concept]
acyclovir monophosphate [Supplementary Concept]
Date introduced: September 9, 1980