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Carboxylesterase
Carboxylesterase is a serine-dependent esterase with wide substrate specificity. The enzyme is involved in the detoxification of XENOBIOTICS and the activation of ester and of amide PRODRUGS.
Year introduced: 2004
CES1P1 protein, human [Supplementary Concept]
RefSeq NR_003276
Date introduced: September 24, 1999
CES1 protein, human [Supplementary Concept]
RefSeq NM_001266
Date introduced: June 12, 2003
carboxylesterase 1A2, human [Supplementary Concept]
GenBank AB187225
Date introduced: May 25, 2007
carboxylesterase 1A1, human [Supplementary Concept]
GenBank AB119997
CES2 protein, human [Supplementary Concept]
RefSeq NM_003869
Date introduced: February 18, 2007
carboxylesterase B1 [Supplementary Concept]
an insecticide resistance-associated esterase
Date introduced: May 4, 2005
Ces1d protein, rat [Supplementary Concept]
RefSeq NM_133295
Date introduced: August 8, 2003
Tok19A1 carboxylesterase [Supplementary Concept]
thermophilic carboxylesterase from Bacillus stearothermophilus; hydrolyzes a range of p-nitrophenyl esters from p-NP acetate to p-NP laurate; N-terminal amino acid sequence given in first source
Date introduced: December 4, 1995
diethyl succinate carboxylesterase [Supplementary Concept]
liver-specific enzyme elevated in plasma of sheep exposed to high copper intake
Date introduced: August 26, 1987
cocaine esterase [Supplementary Concept]
aspect of EC 3.1.1.1, carboxylesterase
Date introduced: January 1, 1968
Masoprocol
A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a lesser extent. It also serves as an antioxidant in fats and oils.
Year introduced: 2014(1987)
7-(p-acetoxyphenylmethyloxy)-3H-phenoxazin-3-one [Supplementary Concept]
a spectroscopic probe for carboxylesterase; structure in first source
Date introduced: April 29, 2012
Monocyte Esterase Deficiency [Supplementary Concept]
Date introduced: November 5, 2012
carboxylesterase 1, mouse [Supplementary Concept]
Date introduced: December 7, 2009
2'-deoxy-N4-(2-(4-nitrophenyl)ethoxycarbonyl)-5-azacytidine [Supplementary Concept]
an inhibitor of DNA methyltransferase that requires activation by human carboxylesterase 1; structure in first source
Date introduced: August 25, 2008
flavone-3,4',7-trihydroxy-3'-methoxy-7-glucoside [Supplementary Concept]
a flavone glucoside from Deverra scoparia that inhibits porcine liver carboxylesterase; structure in first source
Date introduced: May 7, 2008
Ces2c protein, mouse [Supplementary Concept]
RefSeq NM_145603
carboxylesterase Est30, Bacillus [Supplementary Concept]
from Bacillus stearothermophilus
Date introduced: April 19, 2004
acyl-coA hydrolase D1 [Supplementary Concept]
member of the carboxylesterase multigene family; GenBank AB023629 from beagle dog liver microsomes
Date introduced: June 14, 2001