"Megestrol" - MeSH

Select item 680085351.

A progestational hormone used most commonly as the acetate ester. As the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor. It has also been used in the palliative treatment of breast cancer.

Year introduced: 1972(1963)

Select item 680192902.

Megestrol Acetate

Megestrol acetate is a progestogen with actions and uses similar to those of the progestogens in general. It also has anti-androgenic properties. It is given by mouth in the palliative treatment or as an adjunct to other therapy in endometrial carcinoma and in breast cancer. Megestrol acetate has been approved to treat anorexia and cachexia. (From Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995)

Year introduced: 1997

Select item 674750553.

megestrol caproate [Supplementary Concept]

Date introduced: June 27, 2003

Select item 670967514.

PAV-M protocol [Supplementary Concept]

a chemotherapy protocol consisting of cisplatin, adriamycin, etoposide and megestrol acetate; used in the treatment of endometrial carcinoma

Date introduced: December 18, 1995

Select item 670514345.

6-hydroxy-6-methyl-17-acetoxyprogesterone [Supplementary Concept]

impurity isolated from Chinese megestrol; structure given in first source; RN given refers to 6alpha-isomer

Date introduced: March 18, 1987