"Mucin-1" - MeSH

Select item 680183961.

Carbohydrate antigen elevated in patients with tumors of the breast, ovary, lung, and prostate as well as other disorders. The mucin is expressed normally by most glandular epithelia but shows particularly increased expression in the breast at lactation and in malignancy. It is thus an established serum marker for breast cancer.

Year introduced: 2009(1995)

Select item 20166432.

ADAM17 Protein

A disintegrin and metalloproteinase domain-containing protein that cleaves the membrane-bound precursor of TUMOR NECROSIS FACTOR-ALPHA to its mature form. It cleaves several other CELL SURFACE PROTEINS, including INTERLEUKIN-1 RECEPTOR TYPE II; TRANSFORMING GROWTH FACTOR ALPHA; L-SELECTIN; MUCIN-1; and AMYLOID BETA-PROTEIN PRECURSOR. It can also function as an activator of the Notch signaling pathway by mediating the cleavage of NOTCH RECEPTORS.

Year introduced: 2017 (1996)

Select item 675061773.

MUC1 protein, rat [Supplementary Concept]

RefSeq XM_342281

Date introduced: December 14, 2005

Select item 671154394.

BSM1 protein, Bos taurus [Supplementary Concept]

GenBank AF019298

Date introduced: November 20, 1998

Select item 670601925.

MUC1 protein, human [Supplementary Concept]

RefSeq NM_002456