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Phenols
Benzene derivatives that include one or more hydroxyl groups attached to the ring structure.
Chlorophenols
Phenols substituted with one or more chlorine atoms in any position.
Year introduced: 1977
Aminophenols
Phenols substituted in any position by an amino group.
Year introduced: 1979
Polyphenols
A large class of organic compounds having more than one PHENOL group.
Year introduced: 2012 (2010)
Calixarenes
Phenolic metacyclophanes derived from condensation of PHENOLS and ALDEHYDES. The name derives from the vase-like molecular structures. A bracketed [n] indicates the number of aromatic rings.
Year introduced: 2005
Aspalathus
A plant genus of the family FABACEAE. It is the source of an herbal tea that is commonly consumed in South Africa. Members contain aspalathin and other polyphenols (PHENOLS).
Year introduced: 2003
Phenol
An antiseptic and disinfectant aromatic alcohol.
Year introduced: 1998
Propofol
An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
Year introduced: 1990
4-Hydroxybenzoate-3-Monooxygenase
A flavoprotein that catalyzes the synthesis of protocatechuic acid from 4-hydroxybenzoate in the presence of molecular oxygen. EC 1.14.13.2.
Year introduced: 1991(1975)
3-Hydroxyanthranilic Acid
An oxidation product of tryptophan metabolism. It may be a free radical scavenger and a carcinogen.
2,4,5-Trichlorophenoxyacetic Acid
An herbicide with strong irritant properties. Use of this compound on rice fields, orchards, sugarcane, rangeland, and other noncrop sites was terminated by the EPA in 1985. (From Merck Index, 11th ed)
Year introduced: 1974(1971)
2,4-Dichlorophenoxyacetic Acid
An herbicide with irritant effects on the eye and the gastrointestinal system.
Year introduced: 1973(1971)
Glucuronosyltransferase
A family of enzymes accepting a wide range of substrates, including phenols, alcohols, amines, and fatty acids. They function as drug-metabolizing enzymes that catalyze the conjugation of UDPglucuronic acid to a variety of endogenous and exogenous compounds. EC 2.4.1.17.
Year introduced: 1992
Tyrosine Phenol-Lyase
An enzyme that catalyzes the cleavage of tyrosine to phenol, pyruvate, and ammonia. It is a pyridoxal phosphate protein. The enzyme also forms pyruvate from D-tyrosine, L-cysteine, S-methyl-L-cysteine, L-serine, and D-serine, although at a slower rate. EC 4.1.99.2.
Ritodrine
An adrenergic beta-2 agonist used to control PREMATURE LABOR.
Year introduced: 1986(1975)
Probucol
A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
Year introduced: 1991(1973)
Phosphotungstic Acid
Tungsten hydroxide oxide phosphate. A white or slightly yellowish-green, slightly efflorescent crystal or crystalline powder. It is used as a reagent for alkaloids and many other nitrogen bases, for phenols, albumin, peptone, amino acids, uric acid, urea, blood, and carbohydrates. (From Merck Index, 11th ed)
Year introduced: 1968(1964)
Phosphoadenosine Phosphosulfate
3'-Phosphoadenosine-5'-phosphosulfate. Key intermediate in the formation by living cells of sulfate esters of phenols, alcohols, steroids, sulfated polysaccharides, and simple esters, such as choline sulfate. It is formed from sulfate ion and ATP in a two-step process. This compound also is an important step in the process of sulfur fixation in plants and microorganisms.
Pentachlorophenol
An insecticide and herbicide that has also been used as a wood preservative. Pentachlorphenol is a widespread environmental pollutant. Both chronic and acute pentachlorophenol poisoning are medical concerns. The range of its biological actions is still being actively explored, but it is clearly a potent enzyme inhibitor and has been used as such as an experimental tool.
Year introduced: 1991(1971)
p-Hydroxynorephedrine
Parahydroxy analog of phenylpropanolamine with properties as a sympathomimetic.