MeSH

An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.

Year introduced: 1990

Rare and often fatal drug complication which affects patients undergoing long-term treatment with high doses of PROPOFOL. It is characterized by METABOLIC ACIDOSIS; HYPERLIPIDEMIA; RHABDOMYOLYSIS; cardiovascular CIRCULATORY COLLAPSE; CARDIAC FAILURE; and KIDNEY FAILURE.

Year introduced: 2017

a propofol inclusion complex

Date introduced: November 1, 1993

an anticancer stearic acid-based ester conjugate; structure in first source

Date introduced: August 12, 2013

a photoreactive general anesthetic; structure in first source

Date introduced: March 1, 2012

is a relatively stable compound obtained from the reaction between the general anesthetic 2,6 diisopropylphenol (propofol) and nitrosoglutathione (GSNO)

Date introduced: October 4, 2002

a phenobarbital-inducible dog liver P450 enzyme that catalyzes hydroxylation of a broad spectrum of substrates including androstenedione and xenobiotics such as 2,2',4,4',5,5'-hexachlorobiphenyl and propofol; RefSeq NM_001006652

Date introduced: December 5, 1994

J Neurochtargets BCL2L1 (Bcl-xl) and increases vulnerability to propofol in developing astrocytes

Date introduced: June 22, 2017

water-soluble prodrug of propofol

Date introduced: January 25, 2016