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Sulfoxides
Organic compounds that have the general formula R-SO-R. They are obtained by oxidation of mercaptans (analogous to the ketones). (From Hackh's Chemical Dictionary, 4th ed)
Year introduced: 1966
2-Pyridinylmethylsulfinylbenzimidazoles
Compounds that contain benzimidazole joined to a 2-methylpyridine via a sulfoxide linkage. Several of the compounds in this class are ANTI-ULCER AGENTS that act by inhibiting the POTASSIUM HYDROGEN ATPASE found in the PROTON PUMP of GASTRIC PARIETAL CELLS.
Year introduced: 2007
phenothiazine sulfoxidase [Supplementary Concept]
converts ethionamide, chlorpromazine & thioridazine to their corresponding sulfoxides; requires NADPH & oxygen; does not contain P-450
Date introduced: June 23, 1982