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Theophylline
A methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE that degrades CYCLIC AMP thus potentiates the actions of agents that act through ADENYLYL CYCLASES and cyclic AMP.
7-(2-(1-hydroxy-2-butylamino)ethyl)theophylline [Supplementary Concept]
structure given in first source; RN given is for parent cpd
Date introduced: March 15, 1990
Aminophylline
A drug combination that contains THEOPHYLLINE and ethylenediamine. It is more soluble in water than theophylline but has similar pharmacologic actions. It's most common use is in bronchial asthma, but it has been investigated for several other applications.
theodrenaline [Supplementary Concept]
Date introduced: January 1, 1972
theophylline, salbutamol drug combination [Supplementary Concept]
a Russian compound containing 200 mg of theophylline & 8 mg of salbutamol
Date introduced: October 5, 1995
7-(3-deoxy-3-fluorohex-2-enopyranosyl-4-ulose)theophylline [Supplementary Concept]
structure given in first source
Date introduced: September 24, 1992
6-(7-theophylline)-3(2H)-pyridazinone [Supplementary Concept]
structure given in first source; exhibits positive inotropic and bronchospasmolytic action and platelet antiaggregating effects similar to those of theophylline; has lower affinity for A1 and A2 adenosine receptors than theophylline
Date introduced: June 21, 1992
7-(2-(1-methyl-2-phenyl-ethylamino)propyl)theophylline [Supplementary Concept]
structure given in first source; RN given refers to (-)-isomer; RN for cpd without isomeric designation not available 3/92
Date introduced: March 25, 1992
phthalidyltheophylline hydrolase [Supplementary Concept]
breaks C-N bond between theophylline & phthalidyl residues, then hydrolyzes the lactone bond of the phthalidyl moiety to form theophylline & 2-carboxybenzaldehyde
Date introduced: July 14, 1987
phthalidyltheophylline [Supplementary Concept]
less water-soluble than theophylline; prodrug for theophylline
lysine theophylline [Supplementary Concept]
soluble theophylline
Date introduced: April 22, 1983
beta-galactosylumbelliferone theophylline [Supplementary Concept]
used for fluorescent immunoassay
Date introduced: October 7, 1981
8-(4-sulfophenyl)theophylline [Supplementary Concept]
adenosine antagonist
Date introduced: September 15, 1981
theophylline magnesium salicylate [Supplementary Concept]
unique cpd & not a mixture of components as is theophylline calcium salicylate with RN in Chemline: 37287-41-5
Date introduced: April 28, 1981
Tea
The infusion of leaves of CAMELLIA SINENSIS (formerly Thea sinensis) as a beverage, the familiar Asian tea, which contains CATECHIN (especially epigallocatechin gallate) and CAFFEINE.
Year introduced: 1966
7-2-2-(3,4-dihydroxy-phenyl-2-hydroxyethyl-aminoethyl)-theophylline [Supplementary Concept]
derivative of theophylline
Date introduced: March 22, 1999
theophylline oxidase [Supplementary Concept]
catalyzes the oxidation of theophylline to 1,3-dimethyluric acid in the presence of ferricytochrome C
Date introduced: April 8, 1992
theophylline-rutozide [Supplementary Concept]
drug combination consisting of theophylline & rutozide
Date introduced: May 13, 1991
8-(3-sulfophenyl)theophylline [Supplementary Concept]
Date introduced: August 10, 1990
7-(2-bis(2-hydroxyethyl)aminoethyl)theophylline [Supplementary Concept]
RN given refers to parent cpd; structure given in first source
Date introduced: June 26, 1985