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Items: 20

1.

isoprene synthase [Supplementary Concept]

catalyzes the elimination of pyrophosphate from dimethylallyl diphosphate to form isoprene; requires Mg2+ or Mn2+; responsible for leaf isoprene emission into the atmosphere; from aspen leaves; partial amino acid sequence given in first source

Date introduced: June 30, 1995

2.

isoprene [Supplementary Concept]

used in manufacture of ''synthetic'' rubber, butyl rubber; copolymer in production of elastomers; structure

Date introduced: January 1, 1969

3.

Vitamin K 2

A group of substances similar to VITAMIN K 1 which contains a ring of 2-methyl-1,4-naphthoquinione and an isoprenoid side chain of varying number of isoprene units. In vitamin K 2, each isoprene unit contains a double bond. They are produced by bacteria including the normal intestinal flora.

Year introduced: 2002

4.
5.

Hemiterpenes

Compounds that include a single 2-methyl-1,3-butadiene (also known as isoprene) within their structure.

Year introduced: 2004

6.

Triterpenes

A class of terpenes (the general formula C30H48) formed by the condensation of six isoprene units, equivalent to three terpene units.

Year introduced: 1974

7.

Farnesyl-Diphosphate Farnesyltransferase

The first committed enzyme of the biosynthesis pathway that leads to the production of STEROLS. it catalyzes the synthesis of SQUALENE from farnesyl pyrophosphate via the intermediate PRESQUALENE PYROPHOSPHATE. This enzyme is also a critical branch point enzyme in the biosynthesis of ISOPRENOIDS that is thought to regulate the flux of isoprene intermediates through the sterol pathway.

Year introduced: 2006(1975)

8.

Vitamin K 1

A family of phylloquinones that contains a ring of 2-methyl-1,4-naphthoquinone and an isoprenoid side chain. Members of this group of vitamin K 1 have only one double bond on the proximal isoprene unit. Rich sources of vitamin K 1 include green plants, algae, and photosynthetic bacteria. Vitamin K1 has antihemorrhagic and prothrombogenic activity.

Year introduced: use PHYTONADIONE 1964-2001

9.

Dolichols

A class of polyprenols which contain approximately 20 isoprene residues. Although considered ISOPRENOIDS, they terminate with an alpha-saturated isoprenoid group at the hydroxy end of the molecule.

Year introduced: 2020(1975)

10.

styrene-isoprene-styrene block copolymer [Supplementary Concept]

a thermoplastic elastomer

Date introduced: October 3, 2012

11.

poly(isoprene-b-styrene-b-2-vinyl pyridine) [Supplementary Concept]

triblock copolymer

Date introduced: April 25, 2011

12.

poly(isoprene-block-ethylene oxide) [Supplementary Concept]

structure in first source

Date introduced: September 18, 2009

13.

poly(5-(N,N-diethylamino isoprene)) [Supplementary Concept]

structure in first source

Date introduced: February 23, 2009

14.

isoprene monoxide [Supplementary Concept]

Date introduced: August 31, 2005

15.

1,4-polyisoprene [Supplementary Concept]

structure in first source

Date introduced: May 24, 2002

16.

1-hydroxy-2-glutathionyl-2-methyl-3-butene dehydrogenase [Supplementary Concept]

involved in isoprene metabolism in Rhodococcus; amino acid sequence in first source; GenBank AJ249207

Date introduced: April 7, 2000

17.

ISPF protein, E coli [Supplementary Concept]

involved in isoprene biosynthesis; amino acid sequence in first source

Date introduced: November 19, 1999

18.

cis-isoprenyltransferase [Supplementary Concept]

cis-isoprene units of dolichyl monophosphate are added to trans,trans-farnesyl pyrophosphate using isopentenyl pyrophosphate as donor; from embryonic rat brain

Date introduced: January 21, 1994

19.

coenzyme Q10 [Supplementary Concept]

Ubiquinone ring with a chain of 10 isoprene units; redox equilibrium with ubiqunol serving in mitochondrial inner membrane to transfer electrons; presence during reconstitution of acetylcholine receptor into phospholipid vesicles yields vesicles active in catalyzing carbamylcholine-sensitive Na+ flux; coenzyme Q10 depletion has been noted with use of statins

Date introduced: July 15, 1980

20.

Polyprenols

Long chain isoprene compounds that include a hydroxyl group at the terminal carbon atom.

Year introduced: 2020

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