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Items: 5

1.

Capsaicin

An alkylamide found in CAPSICUM that acts at TRPV CATION CHANNELS.

Year introduced: 1984(1975)

2.

TRPV Cation Channels

A subgroup of TRP cation channels named after the vanilloid receptor. They are very sensitive to TEMPERATURE; hot spicy food, and CAPSAICIN. They contain a TRP domain (a five-turn amphipathic helix with an invariant TRYPTOPHAN) and ANKYRIN repeats. Selectivity for CALCIUM over SODIUM ranges from 3 to 100 fold.

Year introduced: 2006(1991)

3.

Carboxylesterase

Carboxylesterase is a serine-dependent esterase with wide substrate specificity. The enzyme is involved in the detoxification of XENOBIOTICS and the activation of ester and of amide PRODRUGS.

Year introduced: 2004

4.

alpha-carboxy-4,5-dimethoxy-2-nitrobenzyl capsaicin [Supplementary Concept]

structure in first source

Date introduced: April 13, 2007

5.

TRPV1 protein, mouse [Supplementary Concept]

GenBank AJ620495

Date introduced: December 11, 2004

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