MeSH

A general class of ortho-dihydroxyphenylalkylamines derived from TYROSINE.

Cell surface proteins that bind catecholamines with high affinity and trigger intracellular changes which influence the behavior of cells. The catecholamine messengers epinephrine, norepinephrine, and dopamine are synthesized from tyrosine by a common biosynthetic pathway.

Year introduced: 1994

Condition where patients present with SYNCOPE and distinct stress-induced TACHYCARDIA without a prolonged QT-interval but heart is structurally normal. Onset occurs in childhood or adolescence and. Germline mutations in the RYR2 gene have been identified. OMIM: 180902

Date introduced: August 25, 2010

GenBank DQ375986

Date introduced: July 2, 2006