MeSH

A technique in which electric pulses, in kilovolts per centimeter and of microsecond-to-millisecond duration, cause a loss of the semipermeability of CELL MEMBRANES, thus leading to ion leakage, escape of metabolites, and increased uptake by cells of drugs, molecular probes, and DNA. Depending on the dosage, the formation of openings in the cell membranes caused by the electric pulses may or may not be reversible.

Year introduced: 1994

The use of a dose of electricity that causes the pores that are formed in CELL MEMBRANES during ELECTROPORATION to remain open long enough to trigger CELL DEATH. It is sometimes used in conjunction with ELECTROCHEMOTHERAPY.

Year introduced: 2023

Treatment modalities that use pulsed electrical currents to permeabilize cell membranes and thereby enhance uptake of substances into cells of the body.

Year introduced: 2023