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Interleukin-2
A soluble substance elaborated by antigen- or mitogen-stimulated T-LYMPHOCYTES which induces DNA synthesis in naive lymphocytes.
Year introduced: 1990(1978)
Interleukin-2 Receptor beta Subunit
A receptor subunit that is a shared component of the INTERLEUKIN 2 RECEPTOR and the INTERLEUKIN-15 RECEPTOR. High affinity receptor complexes are formed with each of these receptors when their respective alpha subunits are combined with this beta subunit and the INTERLEUKIN RECEPTOR COMMON GAMMA-CHAIN.
Year introduced: 2007(2001)
Interleukin-2 Receptor alpha Subunit
A low affinity interleukin-2 receptor subunit that combines with the INTERLEUKIN-2 RECEPTOR BETA SUBUNIT and the INTERLEUKIN RECEPTOR COMMON GAMMA-CHAIN to form a high affinity receptor for INTERLEUKIN-2.
Receptors, Interleukin-2
Receptors present on activated T-LYMPHOCYTES and B-LYMPHOCYTES that are specific for INTERLEUKIN-2 and play an important role in LYMPHOCYTE ACTIVATION. They are heterotrimeric proteins consisting of the INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT, the INTERLEUKIN-2 RECEPTOR BETA SUBUNIT, and the INTERLEUKIN RECEPTOR COMMON GAMMA-CHAIN.
Year introduced: 1990(1989)
Interleukin Receptor Common gamma Subunit
An interleukin receptor subunit that was originally discovered as a component of the INTERLEUKIN 2 RECEPTOR. It was subsequently found to be a component of several other receptors including the INTERLEUKIN 4 RECEPTOR, the INTERLEUKIN 7 RECEPTOR, the INTERLEUKIN-9 RECEPTOR, the INTERLEUKIN-15 RECEPTOR, and the INTERLEUKIN-21 RECEPTOR. Mutations in the gene for the interleukin receptor common gamma chain have been associated with X-LINKED COMBINED IMMUNODEFICIENCY DISEASES.
Year introduced: 2007(2000)
IL2RG protein, human [Supplementary Concept]
RefSeq NM_000206
Date introduced: August 4, 2006
interleukin 2 inhibitor [Supplementary Concept]
MW 11,000 t0 12,000; inhibits IL-2 but not IL-3-dependent proliferation
Date introduced: September 17, 1985
interleukin-2 (22-58) [Supplementary Concept]
a synthetic fragment consisting of amino acids 22-58 contained 100% of the vasopermeability activity of IL-2 and was designated permeability-enhancing peptide (PEP)
Date introduced: June 2, 2003
methionyl interleukin-2, alanine(125)- [Supplementary Concept]
recombinant human interleukin-2 analog
Date introduced: March 27, 1996
interleukin-2 (66-72) [Supplementary Concept]
Date introduced: June 2, 1993
emt protein-tyrosine kinase [Supplementary Concept]
A non-receptor protein tyrosine kinase of the Tec family that participates in the intracellular signaling through antigen receptors such as the T-cell receptor, B-cell receptor, and Fc epsilon; amino acid sequence given in first source; isolated from murine mast cells; RefSeq NM_005546 (human), NM_010583 (mouse); do not confuse with TSK proteoglycan, mouse
Date introduced: May 17, 1993
interleukin-2, succinyl- [Supplementary Concept]
Date introduced: March 12, 1991
interleukin-2, polyethylene glycol-modified [Supplementary Concept]
interleukin-2 (59-72) [Supplementary Concept]
corresponds to 59-82 sequence of secreted human IL-2
Date introduced: October 3, 1985
Interleukin 2 Receptor, Alpha, Deficiency of [Supplementary Concept]
mutation in IL2RA
Date introduced: November 5, 2012
IL2 protein, human [Supplementary Concept]
RefSeq NM_000586
Date introduced: March 13, 2006
Il2rb protein, rat [Supplementary Concept]
RefSeq NM_013195
Il2rb protein, mouse [Supplementary Concept]
RefSeq NM_008368
IL2RB protein, human [Supplementary Concept]
RefSeq NM_000878
Il2ra protein, mouse [Supplementary Concept]
RefSeq NM_008367