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1.

Lactococcus

A genus of gram-positive, coccoid bacteria mainly isolated from milk and milk products. These bacteria are also found in plants and nonsterile frozen and dry foods. Previously thought to be a member of the genus STREPTOCOCCUS (group N), it is now recognized as a separate genus.

Year introduced: 1992

2.

Lactococcus lactis

A non-pathogenic species of LACTOCOCCUS found in DAIRY PRODUCTS and responsible for the souring of MILK and the production of LACTIC ACID.

Year introduced: 1992(1972)

3.

lacticin 481 [Supplementary Concept]

amino acid sequence given in first source; a lantibiotic; GenBank X71410 (L. lactis)

Date introduced: September 3, 1993

4.

LctM protein, Lactococcus lactis [Supplementary Concept]

catalyzes the breakage of eight bonds and formation of six bonds in the synthesis of lacticin 481 from the LctA prepeptide; has been sequenced

Date introduced: February 18, 2004

5.
6.

frr1 protein, Lactococcus lactis [Supplementary Concept]

amino acid sequence in first source; GenBank AJ011960

Date introduced: February 25, 2000

7.

LtrB protein, Lactococcus lactis [Supplementary Concept]

Group II intron-interrupted relaxase; mediates the initiation of conjugal transfer of plasmid pRS01 possibly by introducing a single-stranded nick at the potential origin of transfer, in order to initiate single strand transfer from donor to recipient; the gene encoding this protein is interrupted by a group II intoron, Ll.ltrB; amino acid sequence in first source

Date introduced: July 26, 1996

8.

LtrA protein, Lactococcus lactis [Supplementary Concept]

a multifunctional protein that promotes group II intron splicing and mobility by acting both on RNA and DNA; it has reverse transcriptase for intron duplication maturase to promote splicing, and DNA endonuclease for site-specific cleavage of recipient alleles; isolated from Lactococci lactis; amino acid sequence in first source; Do not confuse with MatR protein, a transcriptional regulator of malonate metabolism

Date introduced: July 26, 1996

9.

dtpT protein, Lactococcus lactis [Supplementary Concept]

from Lactococcus lactis; amino acid sequence given in first source; GenBank U05215

Date introduced: May 18, 1994

10.

lacticin NK34, Lactococcus lactis [Supplementary Concept]

Anti-Bacterial Agents

Date introduced: November 9, 2010

11.

beta-phosphoglucomutase, Lactococcus lactis [Supplementary Concept]

catalyzes conversion of beta-D-glucose-1-phosphate to beta-D-glucose-6-phosphate

Date introduced: August 16, 2006

12.

OpuA protein, Lactococcus lactis [Supplementary Concept]

a glycine-betaine transporter; amino acid sequence in first source; homologies found in many bacterial species

Date introduced: September 5, 2000

13.

BusAA protein, Lactococcus lactis [Supplementary Concept]

a bacterial ABC transporter; amino acid sequence in first source; GenBank AAF04258

Date introduced: November 8, 1999

14.

AldR protein, Lactococcus lactis [Supplementary Concept]

may be involved in regulating isoleucine biosynthesis; isolated from Lactococcus lactis; amino acid sequence in first source; GenBank U92974; do not confuse with AldR protein

Date introduced: October 31, 1997

15.

malate permease protein, Bacteria [Supplementary Concept]

isolated from Leuconostoc oenos; amino acid sequence in first source

Date introduced: May 11, 1996

16.

LagA protein, Lactococcus lactis [Supplementary Concept]

amino acid sequence in first source; do not confuse with LAGA peptide

Date introduced: October 23, 1995

17.

NisT protein, Lactococcus lactis [Supplementary Concept]

a member of the nisA operon in Lactococcus lactis; amino acid sequence in first source; GenBank Z18947

Date introduced: September 1, 1995

18.

NisI protein, Lactococcus lactis [Supplementary Concept]

a member of the nisA operon in Lactococcus lactis; amino acid sequence in first source; GenBank Z18947

Date introduced: September 1, 1995

19.

Bsp6I methyltransferase, Bacillus sp. [Supplementary Concept]

recognizes both 5'-GCGGC-3' and 5'-GCCGC-3'; from plasmid-borne gene bsp6I of Bacillus; 315 amino acids, MW 36.3 kDa; amino acid sequence given in first source; the Bacillus and Lactococcus proteins have identical primary structure organization; GenBank X81638

Date introduced: August 8, 1995

20.

phage infection protein, Lactococcus lactis [Supplementary Concept]

a chromosomal gene product required for phage infection of Lactococcus lactis subsp. lactis C2; 901 amino acid residues, MW 99.4 kDa; amino acid sequence given in first source; GenBank L14679

Date introduced: September 28, 1993

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