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Items: 6

1.

Leiomyoma

A benign tumor derived from smooth muscle tissue, also known as a fibroid tumor. They rarely occur outside of the UTERUS and the GASTROINTESTINAL TRACT but can occur in the SKIN and SUBCUTANEOUS TISSUE, probably arising from the smooth muscle of small blood vessels in these tissues.

Year introduced: FIBROIDS, UTERINE was see UTERINE NEOPLASMS 1991-1993

2.

Leiomyoma, Epithelioid

A relatively rare smooth muscle tumor found most frequently in the wall of the gastrointestinal tract, especially in the stomach. It is similar to other smooth muscle tumors but may become very large and hemorrhage and exhibit small cystic areas. Simple excision is almost always curative. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles and Practice of Oncology, 3d ed, p1354)

Year introduced: 1994

3.

Angiomyoma

A benign tumor consisting of vascular and smooth muscle elements.

Year introduced: 1994

4.

Hereditary leiomyomatosis and renal cell cancer [Supplementary Concept]

A hereditary condition where patients present with cutaneous LEIOMYOMAS (female patients may also have uterine leiomyomas) and are at increased risk for developing KIDNEY NEOPLASMS. Tumors initally appear during adulthood on the skin of the torso, arms, legs, and face and increase in size and number over time; 10% to 16% of patients develop RENAL CELL CARCINOMA. A heterozygous germline mutation in the FH gene has been identified. OMIM: 150800

Date introduced: August 25, 2010

5.
6.

leiomyoma-derived growth factor [Supplementary Concept]

may participate in the pathophysiology of uterine leiomyomas; partial NH2-terminal amino acid (aa) sequence (1-20 aa) was identical to 113-132 aa of the human cysteine-rich protein; amino acid sequence has been determined

Date introduced: September 8, 1995

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