MeSH

A specific opiate antagonist that has no agonist activity. It is a competitive antagonist at mu, delta, and kappa opioid receptors.

Year introduced: 1973(1972)

A pharmaceutical preparation that combines buprenorphine, an OPIOID ANALGESICS with naloxone, a NARCOTIC ANTAGONISTS to reduce the potential for NARCOTIC DEPENDENCE in the treatment of pain. It may also be used for OPIOID SUBSTITUTION THERAPY.

Year introduced: 2016 (2006)

quaternary derivative of naloxone

Date introduced: June 15, 1984

Date introduced: June 16, 1982

Date introduced: February 13, 1995

delta selective opiate antagonist; structure given in first source

Date introduced: March 17, 1988

RN given refers to (5alpha)-isomer

Date introduced: January 1, 1972

Analgesics, Opioid

Date introduced: April 7, 2011

main metabolite of naloxone

Date introduced: April 2, 2007

structure given in first source

Date introduced: February 27, 1989

catalyzes the dehydrogenation of morphine in position 6 to morphinone; also acts on codeine, normorphine and ethylmorphine

Date introduced: June 12, 1985

structure given in first source

Date introduced: November 21, 1983

has high affinity for opiate receptor binding sites; structure given in first source

Date introduced: May 14, 1980