Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Nicotine
Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
Electronic Nicotine Delivery Systems
Devices or objects designed to provide NICOTINE in the form of an inhaled aerosol.
Year introduced: 2018 (2015)
Nicotine Replacement Therapy
Replacing NICOTINE from TOBACCO with an alternate source in order to reduce the severity of tobacco withdrawal during TOBACCO USE CESSATION.
Year introduced: 2024
Nicotine Chewing Gum
Chewing gum which contains NICOTINE.
Year introduced: 2018
Tobacco Use Cessation Devices
Devices or delivery systems used to aid in ending a TOBACCO habit.
Year introduced: 2019(1968)
nicotine 1-N-oxide [Supplementary Concept]
RN given refers to unspecified stereoisomer
Date introduced: May 28, 1980
Tobacco Use Disorder
Tobacco used to the detriment of a person's health or social functioning. Tobacco dependence is included.
Year introduced: 1981
Vaping
Inhaling of vapors produced by ELECTRONIC NICOTINE DELIVERY SYSTEMS such as E-CIGARETTES.
Year introduced: 2017
nicotine imine [Supplementary Concept]
RN given refers to 11C-labeled (S)-isomer
Date introduced: June 22, 1982
nicotine demethylase, tobacco [Supplementary Concept]
expression was highly induced during senescence; GenBank EF042306-7
Date introduced: February 7, 2007
N-methyl-nicotine [Supplementary Concept]
methylated metabolite of nicotine
Date introduced: August 30, 2005
nicotine N-glucuronide [Supplementary Concept]
a metabolite of nicotine
Date introduced: March 14, 1994
nicotine Qbeta vaccine [Supplementary Concept]
a therapeutic vaccine for treating nicotine addiction
Date introduced: May 2, 2007
4-(dimethylphenylsilyl)nicotine [Supplementary Concept]
structure in first source
Date introduced: August 28, 2006
6-(2-phenylethyl)nicotine [Supplementary Concept]
Date introduced: October 3, 2005
6-hydroxynicotine [Supplementary Concept]
Date introduced: July 26, 2005
nicotinic acetylcholine receptor alpha4 subunit [Supplementary Concept]
amino acid sequence given in first source for human neuronal nicotinic receptor alpha4 subunit; GenBank X89741 - X89746
Date introduced: May 28, 1997
nicotine dehydrogenase [Supplementary Concept]
Mo-pterin-Fe-S cluster- & FAD-dependent enzyme composed of 3 unequal polypeptides; catalyzes the conversion of nicotine, acceptor, & water to (S)-6-hydroxynicotine & reduced acceptor
Date introduced: December 4, 1990
nicotine N'-oxidase [Supplementary Concept]
Date introduced: January 13, 1987
nicotine 5'-hydroxylase [Supplementary Concept]