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Inhibitory Activity Assay from US Patent US20240109930: "TRIAZOLYL-METHYL SUBSTITUTED ALPHA-D-GALACTOPYRANOSIDE DERIVATIVES"
Assay data:245 Active, 244 Activity ≤ 1 µM, 245 Tested
SummaryRelated BioAssays by Target
VEGFR ADP GLO Assay from US Patent US20240109917: "PYRAZOLOTHIAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS"
Assay data:23 Active, 13 Activity ≤ 1 µM, 485 Tested
PDGFRβ LanthaScreen Assay from US Patent US20240109917: "PYRAZOLOTHIAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS"
Assay data:478 Active, 11 Activity ≤ 1 nM, 468 Activity ≤ 1 µM, 485 Tested
PDGFRβ HTRF Assay from US Patent US20240109917: "PYRAZOLOTHIAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS"
Assay data:485 Active, 377 Activity ≤ 1 nM, 483 Activity ≤ 1 µM, 485 Tested
Inhibition of the Activity of ACC1 from US Patent US20240109915: "NOVEL ACC INHIBITORS"
Assay data:99 Active, 1 Activity ≤ 1 nM, 99 Activity ≤ 1 µM, 101 Tested
Summary
Mdm2-p53 Inhibition AlphaScreen Assay from US Patent US20240109913: "NEW SPIRO[3H-INDOLE-3,2'-PYRROLIDIN]-2(1H)-ONE COMPOUNDS AND DERIVATIVES AS MDM2-P53 INHIBITORS"
Assay data:56 Active, 55 Activity ≤ 1 µM, 56 Tested
In Vitro CDK7 Assay from US Patent US20240109912: "TRICYCLIC PYRIMIDINES AS CYCLIN-DEPENDENT KINASE 7 (CDK7) INHIBITORS"
Assay data:135 Active, 110 Activity ≤ 1 nM, 131 Activity ≤ 1 µM, 135 Tested
SHP2 Inhibition Enzymatic Assay from US Patent US20240109900: "AZABICYCLIC SHP2 INHIBITORS"
Assay data:519 Active, 511 Activity ≤ 1 µM, 523 Tested
Activity Inhibition Assay on CDK Family Kinases from US Patent US20240109898: "SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE DERIVATIVES, COMPOSITIONS AND PHARMACEUTICAL USES THEREOF"
Assay data:84 Active, 83 Activity ≤ 1 µM, 84 Tested
KRAS G12C-GDP Exchange Assay from US Patent US20240109893: "PREPARATION AND APPLICATION METHOD OF HETEROCYCLIC COMPOUNDS AS KRAS INHIBITOR"
Assay data:22 Active, 8 Activity ≤ 1 nM, 22 Activity ≤ 1 µM, 22 Tested
ADP-Glo Kinase Assay from US Patent US20240109890: "BRIDGED HETEROCYCLYL-SUBSTITUTED PYRIMIDINE COMPOUNDS, PREPARATION METHOD AND MEDICAL USE THEREOF"
Assay data:6 Active, 6 Activity ≤ 1 µM, 6 Tested
KAT6A Biochemical Assay from US Patent US20240109880: "LYSINE ACETYLTRANSFERASE 6A (KAT6A) INHIBITORS AND USES THEREOF"
Assay data:69 Active, 69 Activity ≤ 1 µM, 69 Tested
p300 and CBP Protein Activity Assay from US Patent US20240109879: "BENZIMIDAZOLE COMPOUND AND APPLICATION THEREOF"
Assay data:10 Active, 2 Activity ≤ 1 nM, 10 Activity ≤ 1 µM, 10 Tested
Cereblon Binding Assay from US Patent US20240109877: "PYRIMIDINES FOR DEGRADING BRUTON'S TYROSINE KINASE"
Assay data:14 Active, 5 Activity ≤ 1 µM, 19 Tested
Electrophoretic Mobility Shift Assay (MSA) from US Patent US20240109877: "PYRIMIDINES FOR DEGRADING BRUTON'S TYROSINE KINASE"
Assay data:19 Active, 19 Activity ≤ 1 nM, 19 Activity ≤ 1 µM, 19 Tested
Kinase Assay from US Patent US20240109865: "INDAZOLE COMPOUNDS AS KINASE INHIBITORS"
Assay data:359 Active, 363 Activity ≤ 1 µM, 363 Tested
Enzyme Activity Test from US Patent US20240109861: "SERIES OF PIPERIDINE-SUBSTITUTED BENZOIC ACID COMPOUNDS, AND USE THEREOF"
Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested
ALPK1 In Vitro Kinase Assay from US Patent US20240109853: "ALPHA PROTEIN KINASE 1 INHIBITORS AND METHODS OF USE"
Assay data:448 Active, 434 Activity ≤ 1 µM, 448 Tested
In Vitro DGK Inhibition Assay from US Patent US20240108654: "COMBINATION OF A T CELL THERAPY AND A DGK INHIBITOR"
Assay data:28 Active, 25 Activity ≤ 1 µM, 30 Tested
In Vitro FRET Assay from US Patent US11945784: "IRE1 small molecule inhibitors"
Assay data:65 Active, 56 Activity ≤ 1 nM, 65 Activity ≤ 1 µM, 65 Tested
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