Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Antiviral activity against Lake Victoria marburgvirus - Ci67 in overnight pretreated african green monkey Vero E6 cells after 48 hrs by standard virus yield reduction assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed Citation
Antiviral activity against Lake Victoria marburgvirus - Ravn in overnight pretreated african green monkey Vero E6 cells after 48 hrs by standard virus yield reduction assay
Cytotoxicity against human PBMC after 72 hrs
Assay data:1 Tested
SummaryPubMed Citation
Cytotoxicity against human Hep2 cells after 72 hrs
Cytotoxicity against human A549 cells after 72 hrs
Cytotoxicity against MDCK cells after 72 hrs
Cytotoxicity against human HEK293 cells after 72 hrs
Cytotoxicity against african green monkey Vero E6 cells after 72 hrs
Antiviral activity against Sudan ebolavirus expressing GFP in african green monkey Vero E6 cells after 48 hrs by standard plaque assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Antiviral activity against Zaire ebolavirus expressing GFP in african green monkey Vero E6 cells after 48 hrs by standard plaque assay
Antiviral activity against Ebola-like viruses infected in C57BL/6 mouse spleen assessed as viral antigen at 10 mg/kg, ip single dose measured after 6 days
Antiviral activity against Ebola-like viruses infected in C57BL/6 mouse liver assessed as viral antigen at 10 mg/kg, ip single dose measured after 6 days
Toxicity in Ebola-like viruses infected in C57BL/6 mouse spleen assessed as mild lymphocytolysis at 10 mg/kg, ip single dose measured after 4 days
Toxicity in Ebola-like viruses infected in C57BL/6 mouse assessed as mild hepatitis with hepatocellular necrosis at 10 mg/kg, ip single dose measured after 4 days
Antiviral activity against Ebola-like viruses infected in C57BL/6 mouse assessed as reduction in cytokine IL-6 at 10 mg/kg, ip single dose
Antiviral activity against Ebola-like viruses infected in C57BL/6 mouse assessed as reduction in cytokine TNFalpha at 10 mg/kg, ip single dose
Antiviral activity against Ebola-like viruses infected in C57BL/6 mouse assessed as reduction in cytokine MCP1 at 10 mg/kg, ip single dose
Antiviral activity against Ebola-like viruses infected in C57BL/6 mouse spleen assessed as reduction in viral burden at 10 mg/kg, ip single dose
Antiviral activity against Ebola-like viruses infected in C57BL/6 mouse liver assessed as reduction in viral burden at 10 mg/kg, ip single dose
Antiviral activity against Ebola-like viruses infected in C57BL/6 mouse kidney assessed as reduction in viral burden at 10 mg/kg, ip single dose
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on