PMC

Extent of Genomic NRXN3 Deletions at Chromosomal Region 14q24.3-q31.1
Deletions are shown in red. CNVs detected in control populations (described in this paper) and from the Database of Genomic Variants are also shown. Genomic coordinates and isoform information are from hg18. Control data are as described in this paper.

Pedigrees of Four Unrelated Families with Deletions at the NRXN3 Locus
Black-filled symbols represent ASD-affected individuals, gray-filled symbols represent broader autism phenotype (BAP)-affected individuals, and unfilled symbols represent apparently unaffected individuals. Probands are marked with an arrow. Clinical diagnosis and segregation of the NRXN3 deletions are shown. Children are placed left to right in birth order from eldest to youngest. Other CNVs and genetic variants are found in . Abbreviations are as follows: ADHD, attention deficit hyperactivity disorder; OCD, obsessive compulsive disorder; and NA, not assessed.