Figure 1

Schematic representation of the mechanism of LAMP. (A) Steps in the LAMP reaction. This figure shows the process that starts from primer FIP. However, it should be remembered that DNA synthesis can also begin from primer BIP. (B) Schematic presentation of the structure of LAMP products in a linearized DNA form. B+, B–, F+ and F– stand for the DNA structures shown in the boxes on the left. +, the target sequence flanked by B1 and F1c; –, the complementary sequence.