Fig. 4
Illustration of UTMD-mediated gene transfection and drug delivery to enhance immunotherapy. a) Schematic illustration of mechanism of UTMD-mediated gene transfection. Reprinted with permission from Ref. [130]. Copyright 2020, PNAS. b) Schematic illustration of UTMD-mediated drug delivery to enhance immunotherapy. Exhibited the preparation process of RD@MBs and mechanism of in vivo antitumor immune response induced by RD@MB combined with αPD-L1. Reprinted with permission from Ref. [132]. Copyright 2023, Springer Nature. c) Schematic illustration of UTMD-mediated drug delivery to enhance immunotherapy and the fabrication of immunogenic αPCF MBs and US mediated micro−nano conversion. Reprinted with permission from Ref. [133]. Copyright 2022, American Chemical Society.