Fig. 10

Predicted docking interactions between SAF and monoamine oxidase B (MAO-B). The protein structure was obtained from the Protein Data Bank (ID: 1GOS); the chemical structure of SAF was obtained from PubChem [compound CID: 131682 (3D conformer)]. MAO-B was docked with SAF (yellow dashed box on the left) through PyRx, and the corresponding interaction diagram was generated using LigPlot⁺. The red arcs with spokes radiating toward the ligand (SAF) indicate hydrophobic interactions between SAF and MAO-B. The green dotted line indicates the hydrogen bond between SAF and Pro 104, His 115, or Trp 119, with the corresponding bond lengths being 2.81, 3.16, or 2.90 Å