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Butyrate-mediated Acquisition of TSA Resistance, HCT116-PT and HCT116-BR Cells were Treated with 50–1000 nM TSA for 24 h (A) and 48 h (48) and then Evaluated by MTT Reduction Assay, and the Results are Presented as a Percentage of the Control. Values represent the means ± S.D. (n = 3). *p < 0.05 **p < 0.01 indicate significant differences compared with the untreated control. #p < 0.05 indicates a significant difference in cell viability between the two cell types

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