Dynamic changes of immunocyte subpopulations in thermogenic activation of adipose tissues

Yuqing Ye; Huiying Wang; Wei Chen; Zhinan Chen; Dan Wu; Feng Zhang; Fang Hu

doi:10.3389/fimmu.2024.1375138

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Cibersort analysis of immune cell changes during different cold periods in BAT and SAT. Dynamic expression of naïve CD4⁺T cells (A), naïve CD8⁺T cells (B), memory CD4⁺T cells (C), memory CD8⁺T cells (D), M1 macrophages (E), M2 macrophages (F), Treg cells (G), γδT cells (H), and NK resting cells (I) in different cold periods in BAT and SAT. (J) Correlation analysis of these immune cells in BAT. (K) Correlation analysis of these immune cells in SAT. Statistical data were assessed by unpaired two-tailed Student’s t test. */#P<0.05, **/##P<0.01, ***/###P<0.001, ****/####P<0.0001. BAT, Brown Adipose Tissues; SAT, Subcutaneous Adipose Tissues.