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Table 2

Risk of heart disease or stroke according to blood pressure category

Baseline blood pressure categoryModel 1Model 2Model 3
HR (95% CI)PHR (95% CI)P-valueHR (95% CI)P-value
Composite outcome
 Normotension1.001.001.00
 Prehypertension1.29 (1.13–1.46)< 0.0011.26 (1.11–1.43)< 0.0011.25 (1.10–1.42)0.001
 Hypertension2.15 (1.93–2.40)< 0.0011.95 (1.74–2.18)< 0.0011.52 (1.34–1.74)< 0.001
 P for trend1.49 (1.41–1.57)< 0.0011.41 (1.33–1.49)< 0.0011.23 (1.16–1.32)< 0.001
stroke
 Normotension1.001.001.00
 Prehypertension1.52 (1.20–1.94)0.0011.44 (1.13–1.84)0.0031.41 (1.10–1.81)0.006
 Hypertension3.04 (2.47–3.75)< 0.0012.70 (2.18–3.33)< 0.0012.15 (1.69–2.73)< 0.001
 P for trend1.78 (1.61–1.97)< 0.0011.67 (1.51–1.86)< 0.0011.47 (1.31–1.66)< 0.001
heart disease
 Normotension1.001.001.00
 Prehypertension1.21 (1.05–1.40)0.0101.20 (1.04–1.38)0.0151.19 (1.03–1.38)0.018
 Hypertension2.00 (1.77–2.27)< 0.0011.83 (1.61–2.08)< 0.0011.41 (1.21–1.63)< 0.001
 P for trend1.44 (1.35–1.53)< 0.0011.37 (1.28–1.46)< 0.0011.19 (1.10–1.28)< 0.001

Model 1 crude model. Model 2 adjusted for age and sex. Model 3 adjusted for age, sex, education level, dyslipidemia, BMI, antihypertensive drugs, smoking status, drinking status, diabetes, and site.

CI, confidence interval; HR, hazard ratio.

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