TABLE 9
Immunization and challenge of YF-immune monkeys
| 1st vaccine | 2nd vaccine | Seroconversionc
| Viremia after dengue-2 virus challenged | Mean
| ||
|---|---|---|---|---|---|---|
| Dengue-2 | YF | Peak titera (SD) | Durationb (SD) | |||
| YF 17D | ChimeriVax-D2 | 3/3 | 3/3 | 0/3 | <1.7 | 0 |
| YF 17D | Dengue-2 virus | 4/4 | 4/4 | 0/4 | <1.7 | 0 |
| YF 17D | YF 17D | 0/3 | 3/3 | 3/3 | 4.73 (0.3) | 4 (2) |
| YF 17D | None | 0/2 | 2/2 | 2/2 | 4.60 (0.6) | 5 (0) |
| None | None | 0/2 | 0/2 | 2/2 | 3.55 (1.2) | 5 (0) |
aLog10 FFU/ml.
bDays.
cNumber of monkeys that seroconverted/number of monkeys tested.
dNumber of monkeys with viremia/number of monkeys tested.