Differential Regulation of Tumor Angiogenesis by Distinct ErbB Homo- and Heterodimers

Lily Yen; Naciba Benlimame; Zeng-Rong Nie; Dingzhang Xiao; Taiqi Wang; Ala-Eddin Al Moustafa; Hiroyasu Esumi; Julie Milanini; Nancy E. Hynes; Gilles Pages; Moulay A. Alaoui-Jamali

doi:10.1091/mbc.E02-02-0084

Figure 1

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Characterization of receptor expression in NIH3T3 control and ErbB-transduced cells overexpressing receptor combinations. Immunofluorescence was performed using antibodies for the respective receptors and Texas Red secondary antibodies. Immunofluorescence of NIH3T3 cells transduced with control AP2 (GFP) retrovirus (A), transduced to overexpress single ErbB receptors (B), or transduced with paired ErbB receptor combinations (C). DIC, differential interference contrast.