Generation of a Replication-Competent, Propagation-Deficient Virus Vector Based on the Transmissible Gastroenteritis Coronavirus Genome

Javier Ortego; David Escors; Hubert Laude; Luis Enjuanes

doi:10.1128/JVI.76.22.11518-11529.2002

FIG. 9.

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Quantification of large and small virions in BHK-pAPN cells expressing the TGEV E protein and infected with recombinant virus rTGEV-(MluI-FseI)-FL or rTGEV-Δ3abΔE. Shown are the percentages of intracellular virions with a large (68- to 80-nm diameter) (top) or small (50- to 65-nm) (bottom) core present at 18 and 24 h postinfection. A total of 500 virions were included in the measurements.