Decreasing xanthine oxidase-mediated oxidative stress prevents useful cellular adaptations to exercise in rats

Mari-Carmen Gomez-Cabrera; Consuelo Borrás; Federico V Pallardó; Juan Sastre; Li Li Ji; Jose Viña

doi:10.1113/jphysiol.2004.080564

Figure 6

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Exercise activates ERK1/ERK2 phosphorylation: prevention by allopurinol

A, Western blot analysis of phospho-ERK1/ERK2 in the cytosolic fraction of rat gastrocnemius. B, densitometry analysis of ERK1/ERK2 phosphorylation (n = 3). Values are means ±s.d.**P < 0.01 versus Rest.