PMC full text:
Published online 2003 Jun 12. doi: 10.1073/pnas.1232504100
Table 1.
Summary of aggregation lag times for 70 μM PrPUP and PrPGP in 1 mM sodium phosphate buffer (pH 7.5) and different reducing conditions
| Reducing agent | PrPUP lag time, h | PrPGP lag time, h |
|---|---|---|
| None | 6.9 ± 0.8 | >120 |
| 0.1 mM DTT | 5.9 ± 0.9 | >24 |
| 1.0 mM DTT | 3.4 ± 0.6 | 8.8 ± 0.2 |
| 10.0 mM DTT | 3.4 ± 0.2 | 6.2 ± 0.5 |
| 0.1 mM GSH | 4.6 ± 0.8 | >120 |