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Am J Hum Genet. 1985 Sep; 37(5): 868–872.
PMCID: PMC1684682
PMID: 3876766

Chromosomal localization of the human alpha 1-antitrypsin gene (PI) to 14q31-32.

W T Schroeder, M F Miller, S L Woo, and G F Saunders
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Abstract

In situ hybridization of a recombinant cDNA probe containing the human alpha 1-antitrypsin gene to metaphase chromosomes demonstrated significant hybridization to chromosomal segment 14q31-32. A high percentage of cells analyzed (31%) displayed labeling on chromosome 14. Of all labeled sites on chromosome 14, 60% were found on segment 14q31-32. These results refine the previous assignment of the human alpha 1-antitrypsin gene to segment 14q24.1-32.1.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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