Table 3

Molecular Function of Candidate Selection Genes

Gene ontogeny termHigh FSTLow FST



Total number terms183 31 
Apoptosis regulator1 (0.5%)0 (0.0%)
Cell adhesion molecule4 (2.2%)0 (0.0%)
Cell growth and/or maintenance2 (1.1%)0 (0.0%)
Chaperone2 (1.1%)0 (0.0%)
Defense/immunity protein3 (1.6%)2 (6.5%)
Enzyme50 (27.3%)5 (16.1%)
 Hydrolase11 (6.0%)3 (9.7%)
 Kinase11 (6.0%)0 (0.0%)
 Transferase12 (6.6%)1 (3.2%)
Enzyme regulator4 (2.2%)0 (0.0%)
Ligand binding or carrier57 (31.1%)9 (29.0%)
 Calcium binding7 (3.8%)0 (0.0%)
 Nucleic acid binding23 (12.6%)1 (3.2%)
 Protein binding3 (1.6%)6 (19.4%)
Motor0 (0.0%)1 (3.2%)
Signal transducer27 (14.8%)10 (32.3%)
 Ligand4 (2.2%)1 (3.2%)
 Receptor14 (7.7%)7 (22.6%)
Structural molecule6 (3.3%)2 (6.5%)
Transcriptional regulator9 (4.9%)1 (3.2%)
Transporter18 (9.8%)1 (3.2%)

In the Gene Oncology (GO) classification system, a parent term can have multiple subcategories, or children terms (indented text). For instance, hydrolase, kinase, and transferase are the children of the parent term enzyme. A single gene can have multiple parent and children terms (see Ashburner et al. 2000 for more specific information). Note that percentages sum to 100% for parent terms only. 

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