The fluxes through glycolytic enzymes in Saccharomyces cerevisiae are predominantly regulated at posttranscriptional levels

PMC full text:

Proc Natl Acad Sci U S A. 2007 Oct 2; 104(40): 15753–15758.

Published online 2007 Sep 26. doi: 10.1073/pnas.0707476104

Table 1.

Regulation of glycolytic fluxes and V_max values in yeast in anaerobic compared to aerobic glucose-limited chemostats

Reaction	Hierarchical (ρ_h) and metabolic (ρ_m) regulation of flux			Transcription regulation of V_max		Transcription regulation of flux		Posttranslation regulation of V_max
Reaction	ρ_h	SEM	ρ_m	ρ_{mRNA,V_max}	SEM	ρ_mRNA,flux	SEM	ρ_{PT,V_max}	SEM
HXK	0.50	0.06	0.50	0.45	0.07	0.23	0.02
PGI	0.28	0.03	0.72	0.22	0.11	0.06	0.03	−1.51	0.28
PFK	0.15	0.02	0.85	1.48	0.22	0.22	0.02
FBA	−0.24	0.05	1.24	0.25	0.28	−0.06	0.07	2.20	0.73
TPI	−0.72	0.07	1.72	0.16	0.13	−0.11	0.10	1.13	0.63
TDH	0.42	0.03	0.58	−0.14	0.11	−0.06	0.05	0.18	0.04
PGK	0.38	0.05	0.62	−0.16	0.21	−0.06	0.08	1.78	0.52
PGM	0.35	0.03	0.65	−0.02	0.11	−0.01	0.04	−0.08	0.01
ENO	0.23	0.06	0.77	0.18	0.15	0.04	0.03	−1.18	0.41
PYK	0.45	0.03	0.55	0.25	0.12	0.11	0.05
PDC	0.19	0.02	0.81	0.31	0.16	0.06	0.03	−1.55	0.21
ADH				0.34	0.05