The Short Arm of the Laminin γ2 Chain Plays a Pivotal Role in the Incorporation of Laminin 5 into the Extracellular Matrix and in Cell Adhesion

Laurent Gagnoux-Palacios; Maryline Allegra; Flavia Spirito; Olivier Pommeret; Christine Romero; Jean-paul Ortonne; Guerrino Meneguzzi

doi:10.1083/jcb.153.4.835

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J Cell Biol. 2001 May 14; 153(4): 835–850.

doi: 10.1083/jcb.153.4.835

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Table 2

Alignment of the Laminin γ2 cDNA Sequences Homologous to the Active Site of Fibulin 2 Binding in the Mouse

Mouse	CHAS ADFS V H KITSTFSQDV
Human	CRSSAEYSVHKITSTFHQDV
Dog	CHSSGDYSVHKITSTFHQDV
Horse	CHSSGDYSVHKIISAFHQDV

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The active site of fibulin 2 binding in mouse laminin 5 is underlined. The residues essential to binding are in bold. The dog and horse cDNA sequences are available from EMBL/GenBank/DDBJ under accession nos. AF236864 and AF292647, respectively.