Fig. 11.

Hyperinsulinemic-euglycemic clamps on 5-h-fasted, conscious, unrestrained C57BL/6J mice chronically treated with either vehicle or sildenafil plus arginine subcutaneously for 3 mo. Glucose metabolic index measured using 2[³H]DG is shown for soleus, gastrocnemius, and SVL. Data are means ± SE for 7–8 mice/group. *P ≤ 0.05 vs. vehicle. Data are from Ayala et al. (4).