Oxidative stress and antioxidant defense mechanisms linked to exercise during cardiopulmonary and metabolic disorders

Kelsey Fisher-Wellman; Heather K Bell; Richard J Bloomer

doi:10.4161/oxim.2.1.7732

PMC full text:

Oxid Med Cell Longev. 2009 Jan-Mar; 2(1): 43–51.

doi: 10.4161/oxim.2.1.7732

Copyright/LicenseRequest permission to reuse

Table 5

Acute exercise-induced oxidative stress and cigarette smokers

Reference	Subjects	Exercise	Tissue	Marker	Times	Effects
Surmen-Gur	19 smokers	20 maximal isokinetic knee	blood	MDA	pre, post	↔
(1999)	17 non-smokers	extensions w/nondominant		SOD		↓ in nonsmokers
		leg		GPx		↔
				Vitamin E		↓ in both
Bloomer	14 smokers	GXT	blood	MDA	pre, post	↑ in smokers
(2007)	15 non-smokers			PC		↑ in both
	(all untrained)			8-OHdG		↔
Gochman	14 smokers	GXT	blood	PC	pre, post	↑ in both
(2007)	14 non-smokers			LOOH		↔
	(physically active)			CD		↑ in smokers
				Vitamin A		↔
				Vitamin E		↔

Open in a separate window

Definitions: GSH, reduced glutathione; GSSG, oxidized glutathione; MDA, malondialdehyde; O₂^•−, superoxide radical; TBARS, thiobarbituric acid reactive substances; PC, protein carbonyls; GPx, glutathione peroxidase; TAS, total antioxidant status; TEAC, trolox equivalent antioxidant capacity; H₂O₂, Hydrogen Peroxide; TGSH, total glutathione; TRAP, total radical-trapping antioxidant parameter; XO, xanthine oxidase; SOD, superoxide dismutase; oxLDL, oxidized low density lipoprotein; GR, glutathione reductase; GST, glutathione transferase; CAT, catalase; LOOH, lipid hydroperoxides; 8-OHdG, 8-hydroxydeoxyguanosine; CD, conjugated dienes; ↑, significant increase from pre exercise value; ↓, significant decrease from pre exercise value; ↔, no significant change; numbers following ↑, ↓, ↔, represent respective time points where significant findings occurred.