Interaction between SNPs in selenoprotein P and mitochondrial superoxide dismutase determines prostate cancer risk

Matthew L Cooper; Hans-Olov Adami; Henrik Grönberg; Fredrik Wiklund; Fiona R Green; Margaret P Rayman

doi:10.1158/0008-5472.CAN-08-1827

Figure 1

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The interaction between SOD2 Val16Ala and SEPP1 Ala234Thr SNPs and risk of: A all prostate cancer; B aggressive prostate cancer; C prostate cancer in never-smokers and D prostate cancer in ever-smokers, in the CAPS study. OR = odds ratio, adjusted for age and geographical location. R indicates the referent group (foreground column) for each comparison with the alternative SOD2 genotype group (background column).