Structural basis for synaptic adhesion mediated by neuroligin-neurexin interactions

Xiaoyan Chen; Heli Liu; Ann H. R. Shim; Pamela J. Focia; Xiaolin He

doi:10.1038/nsmb1350

Figure 4

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Alternative splice sites in the NL1-NX1β complex

(a) The locations of the NL1 sites, A and B, and NX1β SS#4 on the surface of the complex. Each residue immediately adjacent to the potential insert is colored green and shown in CPK representation. (b) Calorimetric titration between NL1 without the site B insert and NX1β. (c) Calorimetric titration between NL1 with the site B insert and NX1β. The NL1 protein does not have the site A insert and the NX1β protein does not have the SS#4 insert.