Effect of oral feeding of GTP in TRAMP on serum IGF-I and IGFBP-3 levels. Oral GTP (0.1% in drinking water ad libitum) was initiated in animals at ages representing different stages of the disease as described in the text. A control group that received water alone was run in parallel. At age 32 wk, blood was collected and serum was separated for (A) IGF-I and (B) IGFBP-3 levels.
Mean ± SD.