Table 1
Increased serum FGF21 levels in metabolic disease patients with insulin resistance.
| Disease | Insulin signaling | Serum FGF21 levels |
|---|---|---|
| Nonalcoholic fatty liver disease | Resistance | Increase |
| Type 2 diabetes | Resistance | Increase |
| Obesity | Resistance | Increase |
| Cushing's syndrome | Resistance | Increase |
| Lipodystrophy induced by HIV-1 | Resistance | Increase |
| Endostage renal disease | Resistance | Increase |