Figure 5

(A) Cell body of a control progenitor cell at the radial glial stage migrates away from and then toward the ventricular surface, where it divides. Tracings of cell body positions for six typical controls are shown in panels D,E (green lines). (B,C) Cell body cells transfected with NudC RNAi. Note that the nuclei migrate away from the ventricular surface (C) but they do not move toward the ventricular surface (B) over a 9-h time period. Tracings show these behaviors in D,E (blue lines). Times are shown in hours/minutes. VS, ventricular surface. Scale bar: 20 μm.