Figure 1
Protein-Protein interaction for genes with an observed functional de novo event
Direct protein connections from InWeb, restricting to genes harboring de novo mutations for DAPPLE analysis. Two extensive networks are identified, the first centered on SMARCC2 with 12 connections across 11 genes and the second centered on FN1 with 7 connections across 6 genes. The P-value for each gene having as many connections as those observed color the nodes of the network.