Table 1.

Schedules of controlled substances1

ScheduleDefinitionsExamples
Schedule IHigh abuse potential with no accepted medical use; medications within this schedule may not be prescribed, dispensed, or administeredHeroin, marijuana, ecstasy, gamma hydroxybutyric acid (GHB)

Schedule IIHigh abuse potential with severe psychological or physical dependence; however, these medications have an accepted medical use and may be prescribed, dispensed, or administeredMorphine, codeine, hydrocodone, hydromorphone, methadone, oxycodone, fentanyl, methylphenidate, pentobarbital

Schedule IIIIntermediate abuse potential (ie, less than Schedule II but more than Schedule IV medications)Hydrocodone/acetaminophen 5 mg/500 mg or 10 mg/650 mg; codeine in combination with acetaminophen, aspirin, or ibuprofen; anabolic steroids; ketamine

Schedule IVAbuse potential less than Schedule II but more than Schedule V medicationsPropoxyphene, butorphanol, pentazocine, alprazolam, clonazepam, diazepam, midazolam, phenobarbital, pemoline, sibutramine

Schedule VMedications with the least potential for abuse among the controlled substancesRobitussin AC, Phenergan with codeine
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