The structure of zetekitoxin AB, a saxitoxin analog from the Panamanian golden frog Atelopus zeteki: A potent sodium-channel blocker

Mari Yotsu-Yamashita; Yong H. Kim; Samuel C. Dudley, Jr.; Gaurav Choudhary; Arnold Pfahnl; Yasukatsu Oshima; John W. Daly

doi:10.1073/pnas.0400368101

Fig. 2.

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The 600 MHz ¹³C-¹H gradient HMBC spectra for zetekitoxin AB (0.5 μmol) with ¹H and ¹³C NMR spectra and signal assignments (0.4 ml of CD₃COOD/D₂O, 4:96, 20°C, J_CH = 8 Hz, ¹³C column width for 25,974 Hz). (Inset) ¹³C column width for 6,000 Hz (partial). The gradient HMBC spectra for saxitoxin are in Figs. 6 and 7, which are published as supporting information on the PNAS web site.