The structure of zetekitoxin AB, a saxitoxin analog from the Panamanian golden frog Atelopus zeteki: A potent sodium-channel blocker

Mari Yotsu-Yamashita; Yong H. Kim; Samuel C. Dudley, Jr.; Gaurav Choudhary; Arnold Pfahnl; Yasukatsu Oshima; John W. Daly

doi:10.1073/pnas.0400368101

Fig. 4.

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Representative currents for human heart (hH1A), rat skeletal muscle (μl), and rat brain IIa (rBr2A) sodium channels in Xenopus oocytes in the absence or presence of zetekitoxin AB (ZTX) or saxitoxin (STX). See Methods for details.